Vitamin-D-Derivate und Verfahren zu deren Herstellung

摘要

The invention relates to a vitamin D compound of the general formula wherein: R1 is a hydrogen atom or a hydroxy protecting group; Z is a group of the general formula wherein R2 and R3 are each individually straight or branched, substituted or unsubstituted, (C1-C6)alkyl groups, (C2-C6)alkenyl groups, (C3-C6)cycloalkyl groups or phenyl groups; or wherein R1 and R3 together with the interconnecting oxadimethylene biradical form a 5-7 membered ring-closed (C1-C4)alkyl substituted hemiacetal; with the proviso, that R2 and R3 are not both or individually methyl groups; A and B are each individually hydrogen atoms or methyl groups, or A and B form together a methylene group. The invention also relates to a method of preparing these compounds and to their use in pharmacology. The invention further relates to valuable new intermediates.