发明名称 METHOD OF SYNTHESIS OF 2-(FURYL-2)-1,3-OXAZOLIDINES
摘要 FIELD: organic chemistry. SUBSTANCE: invention relates to a method of synthesis of 2-(furyl-2)-1,3-oxazolidines of the formula (I) <EMI ID=0.558 HE=36 WI=27 TI=CHI> eliciting growth-stimulating activity. 2-(Furyl-2)-1,3-oxazolidines are synthesized by interaction of substituted aminoalcohols of the formula (II) <EMI ID=0.559 HE=21 WI=30 TI=CHI> where R<SP>1</SP>,R<SP>2</SP>,R - H or C<SB>1</SB>-C<SB>4</SB>-alkyl, for example, 2-amino-2-methylpropane-1-ol with furfurol at mole ratio of reagents = 1:1 at the room temperature in the presence of 10% sulfuric acid as a catalyst taken at amount 10 ml/mole furfurol followed by isolation of synthesized compounds by their precipitation from an aqueous suspension or emulsion. EFFECT: increased yield of the end products, simplified process of synthesis and isolation. 1 cl, 13 ex
申请公布号 RU2127272(C1) 申请公布日期 1999.03.10
申请号 RU19970121948 申请日期 1997.12.29
申请人 NIVERSITET;UFIM G NEFTJANOJ TEKHN U 发明人 POKALO E.I.;KHLEBNIKOVA T.D.;KANTOR E.A.
分类号 C07D407/04;C07D413/04;(IPC1-7):C07D407/04 主分类号 C07D407/04
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