| 摘要 |
Phospholipid-analogous compounds of the general formula (I)in which AwhereR1 and R2 are, independently of one another, hydrogen, a saturated or unsaturated acyl or alkyl radical which can optionally be branched or/and substituted, where the total of the carbon atoms in the acyl and alkyl is 16 to 44 C atoms,s is an integer from 0 to 8,c is a radical of a primary or secondary alcohol of the formula RO-, where R is a saturated or unsaturated alkyl radical, mainly with cis double bond, of from 12 to 30 carbon atoms,n is an integer from 2 to 8,R3a can be 1,2-dihydroxypropyl orb can be alkyl with 1 to 3 C atoms when z is>0 orc can be alkyl with 1 to 3 carbon atoms when n<> 2 and z=0,m is 1 or 2,x is an integer from 0 to 8,y is 1 for z=1 to 5 oris 1 to 4 for z=1z is an integer from 0 to 5,are novel and are suitable as liposome constituents, solubilizers and pharmaceuticals. |
