发明名称 |
CANDIDA ALBICANS TWO-COMPONENT HYBRID KINASE GENE, CANIK1, AND USE THEREOF |
摘要 |
A Candida albicans gene, CaNik1, is involved in phenotypic switching which is significant because of a direct correlation between the switching and the level of virulence of the organism. A method of screening for anti-fungal pharmaceutical candidates entails bringing a test substance into contact with cells containing a CaNik1 gene or a variant thereof and then monitoring the effect, if any, on the level of expression of the gene. |
申请公布号 |
WO9855654(A3) |
申请公布日期 |
1999.03.04 |
申请号 |
WO1998US11658 |
申请日期 |
1998.06.05 |
申请人 |
UNIVERSITY OF IOWA RESEARCH FOUNDATION;SRIKANTHA, THYAGARAJAN;SOLL, DAVID, R. |
发明人 |
SRIKANTHA, THYAGARAJAN;SOLL, DAVID, R. |
分类号 |
C12N9/12;C12Q1/68 |
主分类号 |
C12N9/12 |
代理机构 |
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代理人 |
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