发明名称 ANGIOGENESIS PROMOTER
摘要 Neovascularization promoters which contain as the active ingredient compounds represented by general formula (I), wherein R1 represents acyl; R2 represents alkyl; R3 and R4 are the same or different and each represents hydrogen or a hydroxy-protective group; and R5 represents alkyl. These compounds not only have the effect of promoting neovascularization by themselves but also potentiate neovascularization by drugs having neovascularizing effects such as b-FGF. Therefore, there compounds can potentiate the neovascularization in an ischemic tissue or at a site where b-FGF is locally increased due to other pathological factors.
申请公布号 CA2302023(A1) 申请公布日期 1999.03.04
申请号 CA19982302023 申请日期 1998.08.24
申请人 YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD.;MIZUSHIMA, YUTAKA;SEIKAGAKU CORPORATION 发明人 NISHIKAWA, MASAKUNI;KIDO, HIDEAKI;EGI, YASUHIRO;KUBO, YOSHIJI;INOUE, SATORU;HAYASHI, KAZUTAKA
分类号 A61K31/557;A61K31/5575;A61K38/18;A61K45/06;(IPC1-7):A61K31/557 主分类号 A61K31/557
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