摘要 |
<p>Insulin secretion promoters which contain as the active ingredient 4-aminoquinazoline derivatives represented by general formula (I) or pharmacologically acceptable salts thereof wherein R?1A and R1B¿ are the same or different and each represents hydrogen, lower alkyl, lower alkoxy, halogeno, nitro, -NR3R4 (wherein R?3 and R4¿ are the same or different and each represents hydrogen or lower alkyl), etc., or R1A may form together with R1B adjacent thereto -O-(CH¿2?)nO- (wherein n is 1 or 2); Cy represents optionally substituted aryl; R?2¿ represents hydrogen or optionally substituted lower alkyl; and A represents hydrogen or optionally substituted lower alkyl, optionally substituted cycloalkyl, etc., or R2 and A may form together with the nitrogen atom adjacent thereto an optionally substituted heterocycle.</p> |