发明名称 |
Plant rhamnogalacturonan II complexation of heavy metal cations |
摘要 |
The present invention provides rhamnogalacturonan-II (RG-II) and relates to its ability to complex specific multivalent heavy metal cations. In the presence of boric acid, RG-II monomers form dimers that are cross-linked by a borate ester. The yield of such borate ester cross-linked dimers of RG-II is enhanced in the presence of specific heavy metal cations. The present invention further relates to the utility of RG-II in assays for the detection of specific heavy metal contamination; as a reagent useful in the removal of specific heavy metal cations contaminating foods and liquids, for example, fish, wines, etc.; as a pharmaceutical composition useful as an antidote in specific heavy metal cation poisoning; as a treatment for the detoxification of specific heavy metal cations from blood and/or tissues; and in a method of remediation of waters and soils contaminated with specific heavy metal cations.
|
申请公布号 |
US5877164(A) |
申请公布日期 |
1999.03.02 |
申请号 |
US19960755058 |
申请日期 |
1996.11.22 |
申请人 |
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.;INSTITUTE NATIONAL DE LA RECHERCHE AGRONOMIQUE |
发明人 |
O'NEILL, MALCOLM A.;PELLERIN, PATRICE J. M.;WARRENFELTZ, DENNIS;VIDAL, STEPHANE;DARVILL, ALAN G.;ALBERSHEIM, PETER |
分类号 |
A62D3/00;A62D101/43;B09C1/02;B09C1/10;C08B37/00;(IPC1-7):A61K31/715;C07H1/00;G01N33/20 |
主分类号 |
A62D3/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|