摘要 |
An alkoxyphenylalkylamine derivative represented by the following formula: (see. fig I) (wherein X1 and X2 may be either the same or different from each other and each represents a hydrogen atom, a halogen atom, a hydroxyl group, an alkoxy group having 1 to 5 carbon atoms or an alkoxy group having 1 to 5 carbon atoms and substituted with a phenyl group; R1 and R2 may be either the same or different from each other and each represents a hydrogen atom, an alkyl group having 1 to 7 carbon atoms, an alkyl group having 1 to 7 carbon atoms and substituted with "a hydroxyl group, a carboxyl group or an alkoxycarbonyl group" at the end, or, R1 and R2 together with the adjacent nitrogen atom represent a pyrrolidino group, a piperidino group or a piperadino group, all of which may be optionally substituted; A represents a phenyl group, a phenyl group substituted with 1 to 3 substituents arbitrarily selected from "a halogen atom, a hydroxyl group and an alkoxy group having 1 to 5 carbon atoms" or a thienyl group; m is an integer of from 2 to 5; and n is an integer of from 2 to 7), and a salt thereof. The compound of the present invention is useful as a remedy, without causing extrapyramidal disorders, for schizophrenia as well as that for abnormal behaviors accompanying cerebrovascular disorders and senile dementia.
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申请人 |
TAISHO PHARMACEUTICAL CO., LTD. |
发明人 |
NAKAZATO, ATSURO;HATAYAMA, KATSUO;SEKIGUCHI, YOSHINORI;OHTA, KOUMEI;KAWASHIMA, YUTAKA |