发明名称 ALKOXYPHENYLALKYLAMINE DERIVATIVES
摘要 An alkoxyphenylalkylamine derivative represented by the following formula: (see. fig I) (wherein X1 and X2 may be either the same or different from each other and each represents a hydrogen atom, a halogen atom, a hydroxyl group, an alkoxy group having 1 to 5 carbon atoms or an alkoxy group having 1 to 5 carbon atoms and substituted with a phenyl group; R1 and R2 may be either the same or different from each other and each represents a hydrogen atom, an alkyl group having 1 to 7 carbon atoms, an alkyl group having 1 to 7 carbon atoms and substituted with "a hydroxyl group, a carboxyl group or an alkoxycarbonyl group" at the end, or, R1 and R2 together with the adjacent nitrogen atom represent a pyrrolidino group, a piperidino group or a piperadino group, all of which may be optionally substituted; A represents a phenyl group, a phenyl group substituted with 1 to 3 substituents arbitrarily selected from "a halogen atom, a hydroxyl group and an alkoxy group having 1 to 5 carbon atoms" or a thienyl group; m is an integer of from 2 to 5; and n is an integer of from 2 to 7), and a salt thereof. The compound of the present invention is useful as a remedy, without causing extrapyramidal disorders, for schizophrenia as well as that for abnormal behaviors accompanying cerebrovascular disorders and senile dementia.
申请公布号 CA2117250(C) 申请公布日期 1999.03.02
申请号 CA19922117250 申请日期 1992.09.30
申请人 TAISHO PHARMACEUTICAL CO., LTD. 发明人 NAKAZATO, ATSURO;HATAYAMA, KATSUO;SEKIGUCHI, YOSHINORI;OHTA, KOUMEI;KAWASHIMA, YUTAKA
分类号 A61K31/135;A61K31/40;C07C43/23;C07C47/575;C07C59/68;C07C217/56;C07C217/60;C07C217/62;C07C229/14;C07D213/74;C07D239/42;C07D295/08;C07D295/096;C07D333/16;(IPC1-7):C07C217/56;C07D401/04;C07D403/04;C07D243/08;C07D409/12;C07D333/20;C07D239/26;C07D213/38 主分类号 A61K31/135
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