MONOCLONAL ANTIBODIES SPECIFIC TO HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR AND THERAPEUTIC METHODS EMPLOYING SAME

摘要

Monoclonal antibodies and hybrid cell lines for production of monoclonal antibodies specific to the human epidermal growth factor receptor which are capable of inhibiting the growth of human tumor cells expressing human epidermal growth factor receptors are provided. Therapeutic compositions containing these monoclonal antibodies by themselves and in combination with anti-neoplastic agents are also disclosed.