| 摘要 |
PCT No. PCT/GB95/01766 Sec. 371 Date Jan. 24, 1997 Sec. 102(e) Date Jan. 24, 1997 PCT Filed Jul. 26, 1995 PCT Pub. No. WO96/03657 PCT Pub. Date Feb. 8, 1996A solution phase assay of glycated proteins, such as glycated haemoglobin and plasma-soluble glycated proteins, is carried out by reacting the assay sample with a photoluminescent or chemiluminescent marker compound containing a boronic acid group which reacts selectively with the glycated protein. The luminescence of the marker compound is excited at a wavelength at which it is preferentially quenched by the binding of the marked compound to the glycated protein. The quenching in luminescence gives a measure of the degree of glycation of the glycated proteins.
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