发明名称 |
Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives |
摘要 |
Novel derivatives of 1-aminoindan and their salts are described. Optically active 1-aminoindan derivatives are prepared by reacting a N-benzyl analog of the desired compound with an enantiomer of mandelic acid. Parkinson's disease, dementia, epilepsy, convulsions, or seizures are treated by administering a compound of the formula: <IMAGE>
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申请公布号 |
US5877221(A) |
申请公布日期 |
1999.03.02 |
申请号 |
US19970953097 |
申请日期 |
1997.10.17 |
申请人 |
TEVA PHARMACEUTICAL INDUSTRIES, LTD.;TECHNION RESEARCH AND DEVELOPMENT FOUNDATION, LTD. |
发明人 |
COHEN, SASSON;HERZIG, YAACOV;LEVY, RUTH;STERLING, JEFF;VEINBERG, ALEX;YOUDIM, MOUSSA B. H.;FINBERG, JOHN P. M. |
分类号 |
A01N37/18;A01N37/34;A61K31/135;A61K31/137;A61K31/16;A61K31/165;A61K31/166;A61K31/167;A61K31/18;A61K31/195;A61K31/196;A61K31/215;A61K31/216;A61K31/24;A61K31/27;A61K31/275;A61K31/277;C07C209/04;C07C209/88;C07C211/00;C07C211/38;C07C211/42;C07C213/10;C07C215/44;C07C217/74;C07C231/20;C07C233/05;C07C233/06;C07C233/23;C07C233/74;C07C237/04;(IPC1-7):A61K31/16 |
主分类号 |
A01N37/18 |
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地址 |
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