Perfluorinated resins as a support for solid phase reactions

摘要

A polytetrafluoroethylene resin bearing a reactive functional group comprising a side chain having a sulphonamide or sulphonanilimide moiety like the one of formula (I): wherein n and m are each integers of from 1 to several hundred, m is a spacer group; Y is a spacer group; R is a linear or branched C1-6 aliphatic hydrocarbon group, optionally interrupted by heteroatoms; R is an aryl group, substituted by a reactive functional moiety such as a carboxy group, carboxyl group, sulphonyl group, amine, amide, thioester or the like. This resin is particularly useful in solid phase synthesis and in the manufacture of microreactors.