摘要 |
Compound of the formula (I):wherein:R is defined in the specification;each R', independently of the other, is H, acetyl, benzyl, methoxymethyl, tosyl, mesyl, trifluoromesyl, tri(C1-4 alkyl)silyl, di(C1-4 alkyl)phenylsilyl, diphenyl(C1-4 alkyl)silyl, or triphenylsilyl, or both R together from an alkylidene protecting group;R'' is H, acetyl, benzyl, methoxymethyl, tosyl, mesyl, trifluoromesyl, tri(C1-4 alkyl)silyl, di(C1-4 alkylsilyl)phenylsilyl, diphenyl(C1-4 alkyl)silyl, or triphenylsilyl;X is H, Cl, Br, or R4 (where R4 is C1-22-alkyl);Y is H, Cl, Br, or -CHR2OH, -CR2R3OH, -CH2CHR2OH, -CH2CR2R3OH, -SR2, -SeR2, -OH, -NH2, -R5 (where R2, R3, and R5 are independently of each other C1-22-alkyl);or X and Y together form a covalent bond;A and A' are both H or together A and A' form =O,are useful as anticancer agents and as glycosidase inhibitors. |