发明名称 TOPICAL PHARMACEUTICAL COMPOSITIONS COMPRISING A FK506 CLASS COMPOUND, AN UNSATURATED FATTY ALCOHOL, WATER AND DIETHER ALCOHOL, ALKANEDIOL OR ETHER DIOL AS A SOLVENT
摘要 This invention provides a topical composition, in the form of an emulsion, that comprises a compound of the FK506 class; a physiologically acceptable alkanediol, ether diol or diether alcohol containing up to 8 carbon atoms as solvent for the compound of the FK506 class; an unsaturated fatty alcohol and water. In another aspect, this invention provides a topical pharmaceutical composition that comprises a macrolide in suspension. In a further aspect, this invention provides the use of an unsaturated fatty alcohol to stabilise a macrolide in a pharmaceutical composition.
申请公布号 NZ295170(A) 申请公布日期 1999.02.25
申请号 NZ19950295170 申请日期 1995.10.26
申请人 NOVARTIS AG (SUBSTITUTED UNDER SECTION 24(1) FOR SANDOZ LTD) 发明人 JACKMAN, MARTIN;POPP, XUE-PING;RICHTER, FRIEDRICH;SCHMOOK, FRITZ
分类号 A61K9/107;A61K9/00;A61K31/395;A61K31/436;A61K31/55;A61K47/00;A61K47/06;A61K47/10;A61K47/14;(IPC1-7):A61K31/55 主分类号 A61K9/107
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