发明名称 |
TOPICAL PHARMACEUTICAL COMPOSITIONS COMPRISING A FK506 CLASS COMPOUND, AN UNSATURATED FATTY ALCOHOL, WATER AND DIETHER ALCOHOL, ALKANEDIOL OR ETHER DIOL AS A SOLVENT |
摘要 |
This invention provides a topical composition, in the form of an emulsion, that comprises a compound of the FK506 class; a physiologically acceptable alkanediol, ether diol or diether alcohol containing up to 8 carbon atoms as solvent for the compound of the FK506 class; an unsaturated fatty alcohol and water. In another aspect, this invention provides a topical pharmaceutical composition that comprises a macrolide in suspension. In a further aspect, this invention provides the use of an unsaturated fatty alcohol to stabilise a macrolide in a pharmaceutical composition.
|
申请公布号 |
NZ295170(A) |
申请公布日期 |
1999.02.25 |
申请号 |
NZ19950295170 |
申请日期 |
1995.10.26 |
申请人 |
NOVARTIS AG (SUBSTITUTED UNDER SECTION 24(1) FOR SANDOZ LTD) |
发明人 |
JACKMAN, MARTIN;POPP, XUE-PING;RICHTER, FRIEDRICH;SCHMOOK, FRITZ |
分类号 |
A61K9/107;A61K9/00;A61K31/395;A61K31/436;A61K31/55;A61K47/00;A61K47/06;A61K47/10;A61K47/14;(IPC1-7):A61K31/55 |
主分类号 |
A61K9/107 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|