发明名称 PROCESS FOR THE PREPARATION OF A MAGNESIUM SALT OF A SUBSTITUTED SULPHINYL HETEROCYCLE
摘要 PCT No. PCT/SE97/00674 Sec. 371 Date Jul. 10, 1997 Sec. 102(e) Date Jul. 10, 1997 PCT Filed Apr. 22, 1997 PCT Pub. No. WO97/41114 PCT Pub. Date Nov. 6, 1997A novel process for the preparation of a magnesium salt of Formula I of a substituted sulfinyl heterocyclic compound containing an imidazole moiety. The process is carried out by mixing the substituted heterocycle of formula I with a weak and a magnesium source. The base and the magnesium source are selected to result in residues which are easy to remove during the reaction. The invention also relates to the use of the produced compounds in medicine.
申请公布号 EP0897386(A1) 申请公布日期 1999.02.24
申请号 EP19970921045 申请日期 1997.04.22
申请人 ASTRA AKTIEBOLAG 发明人 HOEGBERG, JAN-AKE;IOANNIDIS, PANAGIOTIS;MATTSON, ANDERS
分类号 A61K31/00;A61K31/415;A61K31/44;A61K31/4427;A61K31/4439;A61P1/00;A61P1/04;C07D235/28;C07D401/12 主分类号 A61K31/00
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