发明名称 |
Triple helices and processes for making same |
摘要 |
Oligonucleotides and processes for their use for specific recognition of a target sequence in double-stranded nucleic acid through the formation of a triple helix. The oligonucleotides can bind in a parallel or antiparallel orientation to one of the strands of the target sequence depending upon the sequence composition of the target sequence and oligonucleotide used. The oligonucleotides are used as diagnostic or therapeutic agents through incorporation of an appropriate moiety in one or more nucleotides in the triple helix forming oligonucleotide.
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申请公布号 |
US5874555(A) |
申请公布日期 |
1999.02.23 |
申请号 |
US19930156957 |
申请日期 |
1993.11.22 |
申请人 |
CALIFORNIA INSTITUTE OF TECHNOLOGY |
发明人 |
DERVAN, PETER B.;MOSER, HEINZ E. |
分类号 |
C12Q1/68;(IPC1-7):C07H21/04 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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