发明名称 |
Lipid vesicles formed with alkylammonium fatty acid salts |
摘要 |
A liposome for use in encapsulating both hydrophobic and hydrophilic substances (i.e., a "payload"),is disclosed which is capable of delivering their load upon the occurrence of a trigger or control condition. The liposomes are formed to stably encapsulate a particular active agent to form a delivery vehicle for the agent. The liposomes of the delivery vehicle are stable in a particular environment but become unstable or permeable if passed from the stable environment (e.g., characteristic of a particular pH and/or temperature and/or ionic strength) to a changed or unstable environment, thereby delivering their payload.
|
申请公布号 |
US5874105(A) |
申请公布日期 |
1999.02.23 |
申请号 |
US19960594175 |
申请日期 |
1996.01.31 |
申请人 |
COLLABORATIVE LABORATORIES, INC. |
发明人 |
WATKINS, DAVID C.;VICHROSKI, THOMAS J.;HAYWARD, JAMES A. |
分类号 |
A61K9/127;(IPC1-7):A61K9/127 |
主分类号 |
A61K9/127 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|