| 摘要 |
An immuno-suppressive agent containing, as an effective component, an enopyranose derivative of the following formula (I) or its salt: wherein R1l is a hydrogen atom, alkyl which may be substituted, alkenyl, alkynyl, -OSO2R7, a halogen atom, -OCOR7, -NHCOR8, alkoxy, phenyl which may be substituted or a saccharose residue, R2 is a hydrogen atom or alkyl, R3 is a hydrogen atom or a halogen atom, R4 is a hydrogen atom, -COR9, silyl which may be substituted or alkyl which may be substituted, one of R5 and R6 is hydroxyl, alkoxy which may be substituted, a saccharose residue, cycloalkyloxy which may be substituted or -OCOR10 and the other is a hydrogen atom or alkyl which may be substituted, or R4 and R5 together form a single bond, while R6 is a hydrogen atom or alkyl which may be substituted, each of R7, R9 and R10 is alkyl or phenyl which may be substituted, R8 is alkyl, phenyl which may be substituted or benzyloxy, X is a hydrogen atom, alkyl which may be substituted, alkenyl which may be substituted, alkynyl which may be substituted, cycloalkyl which may be substituted, phenyl which may be substituted, pyridyl which may be substituted, furanyl which may be substituted, thienyl which may be substituted, formyl, -COR11, -C(W1)W2R11 or -SO2R11, R11 is a chain hydrocarbon group which may be substituted, a monocyclic hydrocarbon group which may be substituted, a polycyclic hydrocarbon group which may be substituted, a monocyclic heterocycle group which may be substituted, or a polycyclic heterocycle group which may be substituted, W1 is an oxygen atom or a sulfur atom, W2 is an oxygen atom, a sulfur atom or -NH-, Y is a hydrogen atom, alkyl which may be substituted, alkenyl which may be substituted or alkynyl which may be substituted.
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