RNA transcript of human cholesteryl ester transfer protein gene
摘要
An RNA transcript of the human cholesteryl ester transfer protein (CETP) gene having a 5' untranslated region including a regulatory sequence is new. Also claimed are: (1) a method (a) for identifying substances capable of inhibiting CETP gene expression, comprising measuring the translation rate of the above transcript in the presence of a test substance; (2) a test substance capable of inhibiting CETP gene expression; (3) an antisense oligonucleotide capable of binding to the 5' untranslated region of the above transcript; and (4) a method based on surface plasmon resonance for measuring the binding of a substance to a nucleic acid.
申请公布号
DE19731609(A1)
申请公布日期
1999.02.18
申请号
DE19971031609
申请日期
1997.07.23
申请人
BOEHRINGER INGELHEIM PHARMA KG, 55218 INGELHEIM, DE