This invention relates to a key intermediate in the synthesis of an endothelin antagonist the synthesis of this key intermediate via an asymmetric conjugate addition reaction.
申请公布号
WO9907367(A1)
申请公布日期
1999.02.18
申请号
WO1998US16251
申请日期
1998.08.04
申请人
MERCK & CO., INC.;DEVINE, PAUL, N.;HEID, RICHARD, M., JR.;TILLYER, RICHARD, D.;TSCHAEN, DAVID, M.
发明人
DEVINE, PAUL, N.;HEID, RICHARD, M., JR.;TILLYER, RICHARD, D.;TSCHAEN, DAVID, M.
