发明名称 |
DETERMINING THE TRANSFORMING CAPABILITY OF AGENTS |
摘要 |
The invention relates to activation of apoptin-induced apoptosis by different cell-transforming agents in normal and/or cancer-prone cells. Apoptin or also called VP3 is a viral protein derived from the Chicken anemia virus. Also the invention relates to preventive anti-tumor therapies of normal and/or cancer-prone cells. Treatment of normal and/or cancer-prone cells with tumor-inducing agents will activate apoptin-induced apoptosis, resulting in the elimination of potential tumor cells. Also the invention relates to diagnosis of cancer agents. Agents with tumor activity can be examined by expressing them in normal cells and analyzing their capability of enabling apoptin-induced apoptosis.
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申请公布号 |
WO9908108(A1) |
申请公布日期 |
1999.02.18 |
申请号 |
WO1998NL00457 |
申请日期 |
1998.08.11 |
申请人 |
LEADD B.V.;NOTEBORN, MATHIEU, HUBERTUS, MARIA |
发明人 |
NOTEBORN, MATHIEU, HUBERTUS, MARIA |
分类号 |
C12Q1/00;G01N33/15;G01N33/50;G01N33/574;G01N33/68;(IPC1-7):G01N33/50 |
主分类号 |
C12Q1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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