发明名称 |
ANTIFREEZE PROTEINS, DNA AND EXPRESSION SYSTEMS |
摘要 |
§& he winter rye, upon cold-induction or aclimation, produces a family of antifreeze proteins that are similar to pathogen-related proteins. Two of these proteins, both of which are chitinase-like proteins, are cloned using molecular biology techniques and are expressed in bacterial and yeast (Pichia) systems and Arabidopsis thaliana. The recombinant proteins showed both chitinase and antifreeze activities. The invention includes the DNA and protein sequences of the chitinase-like antifreeze proteins, any modifications of the said sequences, the expression of these proteins and their appplication in agriculture, food industry and medicine. |
申请公布号 |
WO9906565(A2) |
申请公布日期 |
1999.02.11 |
申请号 |
WO1998CA00745 |
申请日期 |
1998.07.31 |
申请人 |
ICE BIOTECH INC.;HEW, CHOY;XIONG, FEI;MOFFATT, BARBARA;GRIFFITH, MARILYN |
发明人 |
HEW, CHOY;XIONG, FEI;MOFFATT, BARBARA;GRIFFITH, MARILYN |
分类号 |
A61K38/00;C07K14/415;C12N1/21;C12N9/24;C12N15/29;C12N15/82 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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