发明名称 |
SUPERNUCLEOPHILIC 4-SUBSTITUTED-PYRIDINE CATALYSTS, AND PROCESSES USEFUL FOR PREPARING SAME |
摘要 |
Described are preferred processes for producing extrusion-granulated supernucleophilic 4-amino-substituted pyridine catalysts, and granular products obtainable thereform. Also described are preferred activationsubstitution-deactivation processes for producing 4-aminopyridine compounds, which involve the use of acrylic acid or acrylamide or analogs thereof for activation, and substitution steps conducted under mild basic conditions in an excess of the amine reagent for 4-substitution. Such processes provide improved reacted masses which are more readily processed to recover the products in pure, heat-stable form. Further, described are processes for preparing 4-substituted-pyridines via pyridine betaines.
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申请公布号 |
CA2298821(A1) |
申请公布日期 |
1999.02.11 |
申请号 |
CA19982298821 |
申请日期 |
1998.07.31 |
申请人 |
REILLY INDUSTRIES, INC. |
发明人 |
BALASUBRAMANIAN, MARUDAI;HUCKSTEP, L. MARK;CALVIN, JOEL R.;HOPPER, CHARLES R.;CURTIS, JOE W.;SCRIVEN, ERIC F.V.;MURUGAN, RAMIAH |
分类号 |
C07D213/74;B01J31/02;B01J35/02;B01J37/00;C07D213/73;C07D213/84;(IPC1-7):C07D213/02 |
主分类号 |
C07D213/74 |
代理机构 |
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