发明名称 |
METHODS FOR TREATING NEUROLOGICAL DEFICITS |
摘要 |
The present invention features methods and compositions for treating a patient who has a neurological deficit. The method can be carried out, for example, by contacting (in vivo or in culture) a neural progenitor cell of the patient's central nervous system (CNS) with a polypeptide that binds the epidermal growth factor (EGF) receptor and directing progeny of the proliferating progenitor cells to migrate en masse to a region of the CNS in which they will reside and function in a manner sufficient to reduce the neurological deficit. The method may include a further step in which the progeny of the neural precursor cells are contacted with a compound that stimulates differentiation.
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申请公布号 |
CA2298506(A1) |
申请公布日期 |
1999.02.11 |
申请号 |
CA19982298506 |
申请日期 |
1998.08.04 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
REID, JAMES STEVEN;FALLON, JAMES H. |
分类号 |
A61K45/06;A61K38/00;A61K38/18;A61K38/22;A61P25/28;A61P27/02;(IPC1-7):A61K38/02 |
主分类号 |
A61K45/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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