发明名称 NEW 2,3-BENZODIAZEPINE DERIVATIVES
摘要 The invention relates to new tricyclic 2,3-benzodiazepine derivatives of general formula (I), stereoisomers and acid addition salts thereof and to pharmaceutical compositions containing the same, wherein the main substituent meanings are as follows: R<1> and R<2> represent independently hydrogen, halogen, a C1-4 alkyl, C1-4 alkoxy, nitro, trifluoromethyl or optionally substituted amino group, X represents hydrogen or chlorine atom, Y represents chlorine or bromine atom, A represents a 5-membered heterocyclic group containing 1 to 3 nitrogen atoms. The compounds are suitable for treating conditions associated with muscle spasms, epilepsy as well as acute and chronic forms of neurodegenerative diseases.
申请公布号 WO9906408(A1) 申请公布日期 1999.02.11
申请号 WO1998HU00071 申请日期 1998.07.27
申请人 GYOGYSZERKUTATO INTEZET KFT.;ABRAHAM, GIZELLA;CSUZDI, EMESE;SOLYOM, SANDOR;BERZSENYI, PAL;TARNAWA, ISTVAN;ANDRASI, FERENC;LING, ISTVAN;HAMORI, TAMAS;HORVATH, KATALIN;MORAVCSIK, IMRE;PALLAGI, ISTVAN;SIMAY, ANTAL 发明人 ABRAHAM, GIZELLA;CSUZDI, EMESE;SOLYOM, SANDOR;BERZSENYI, PAL;TARNAWA, ISTVAN;ANDRASI, FERENC;LING, ISTVAN;HAMORI, TAMAS;HORVATH, KATALIN;MORAVCSIK, IMRE;PALLAGI, ISTVAN;SIMAY, ANTAL
分类号 A61K31/551;A61P9/10;A61P21/02;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/20;A61P25/24;A61P25/28;A61P25/30;A61P25/32;A61P43/00;C07D487/04;(IPC1-7):C07D487/04;A61K31/55 主分类号 A61K31/551
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