| 发明名称 |
INTRACELLULAR PRODUCTION OF HEPATITIS C E1 AND E2 TRUNCATED POLYPEPTIDES |
| 摘要 |
Methods for obtaining recombinantly produced, C-terminally truncated, E1 and E2 polypeptides from cell lysates are disclosed. The intracellularly expressed truncated molecules display improved biological properties as compared to their secreted counterparts. |
| 申请公布号 |
WO9850556(A3) |
申请公布日期 |
1999.02.11 |
| 申请号 |
WO1998US09097 |
申请日期 |
1998.05.06 |
| 申请人 |
CHIRON CORPORATION |
发明人 |
HOUGTON, MICHAEL;CHOO, QUI-LIM;ABRIGNANI, SERGIO;CHIEN, DAVID;SELBY, MARK;GLAZER, EDWARD |
| 分类号 |
G01N33/576;A61K39/00;A61K39/29;A61P31/14;C07K1/22;C07K14/18;C12N15/08;C12N15/09;C12N15/40;C12P21/02 |
主分类号 |
G01N33/576 |
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