摘要 |
Aryloxyaniline derivatives represented by the general formula (I), wherein Ar<1> and Ar<2> represent each a substituted or unsubstituted phenyl, pyridyl, or naphthyl group; R<1> represents a hydrogen atom, an alkyl group or the like; X<1> represents a hydrogen atom, an alkyl group or the like; and Y<1> represents a branched or unbranched 1-6 C alkylene group or a single bond, or pharmaceutically acceptable salts thereof. The derivatives can provide medicines having high affinity for MDR exhibiting therapeutic and prophylactic effects on anxiety and associated diseases, depression, and the like.
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申请人 |
TAISHO PHARMACEUTICAL CO., LTD.;NIHON, NOHYAKU CO., LTD.;NAKAZATO, ATSURO;OKUBO, TAKETOSHI;NAKAMURA, TOSHIO;CHAKI, SHIGEYUKI;TOMISAWA, KAZUYUKI;NAGAMINE, MASASHI;YAMAMOTO, KENJI;HARADA, KOICHIRO;YOSHIDA, MASANORI |
发明人 |
NAKAZATO, ATSURO;OKUBO, TAKETOSHI;NAKAMURA, TOSHIO;CHAKI, SHIGEYUKI;TOMISAWA, KAZUYUKI;NAGAMINE, MASASHI;YAMAMOTO, KENJI;HARADA, KOICHIRO;YOSHIDA, MASANORI |