发明名称 |
DRY METHOD FOR PREPARING PARTICLES BASED ON ACTIVE PRINCIPLES, DRY PARTICLES PREPARED BY THIS METHOD, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH PARTICLES |
摘要 |
FIELD: pharmaceutical industry. SUBSTANCE: invention relates to dry preparation of essentially spherical particles consisting of high-activity substance introduced into biologically compatible polymer with high boiling temperature, this polymer and above-mentioned high-activity substance being admixed under stirring to immiscible homogeneous viscous carrier. Stirring is continued until formation of biologically compatible polymer microbeads and complete introduction of high-activity substance into them are attained. Temperature of this process is not higher than vitrification temperature of polymer. EFFECT: enabled formation of microbeads with load on core material more than 15% and which have no high-activity substance on their surfaces. 16 cl, 10 ex
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申请公布号 |
RU2125869(C1) |
申请公布日期 |
1999.02.10 |
申请号 |
RU19940016386 |
申请日期 |
1994.05.13 |
申请人 |
SOS'ETE DE KONSEJ DE RESHERSH EH D' APPLIKAS'ON S';JANTIFIK |
发明人 |
RJUIZ ZHAN-MARK |
分类号 |
A61K9/50;A61J3/00;A61K9/16;A61K9/20;A61K9/22;A61K9/52;B01J13/02;B01J13/04;C08F2/04;(IPC1-7):A61K9/20 |
主分类号 |
A61K9/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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