Enhanced scopolamine production in (hyoscyamus) plants and hairy root cultures

摘要

The present invention relates to regulation of tropane alkaloid biosynthesis in solanaceous plants. More specifically, the present invention relates to genetically engineered scopolamine-rich hairy root cultures of Hyoscyamus muticus, as well as whole H. muticus plants. This invention thus provides specific means for markedly enhancing the productivity of scopolamine, a pharmaceutically important secondary metabolite.