| 发明名称 |
CELLULAR VESICLE CALLED ''EXOSOME'', PREPARATION AND USE THEREOF IN IMMUNE STIMULATION |
| 摘要 |
The invention concerns a novel method for sensitising antigen-presenting cells, novel means for implementing the method, and novel membrane vesicles with immunogenic properties. The invention concerns particularly texosomes (vesicles derived from tumour cells ) and dexosomes (vesicles derived from dendritic cells loaded with antigens or not), and their use for vectoring and presenting antigens in vitro or in vivo and methods or compositions for treating cancers, infectious, parasitic or autoimmune diseases in particular. |
| 申请公布号 |
WO9903499(A1) |
申请公布日期 |
1999.01.28 |
| 申请号 |
WO1998FR01431 |
申请日期 |
1998.07.03 |
| 申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;INSTITUT GUSTAVE ROUSSY;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;INSTITUT CURIE;ZITVOGEL, LAURENCE;RAPOSO, GRACA;REGNAULT, ARMELLE;AMIGORENA, SEBASTIAN |
发明人 |
ZITVOGEL, LAURENCE;RAPOSO, GRACA;REGNAULT, ARMELLE;AMIGORENA, SEBASTIAN |
| 分类号 |
C12N5/06;A61K35/12;A61K35/14;A61K35/23;A61K38/17;A61K39/00;A61K39/12;A61P31/00;A61P33/00;A61P35/00;A61P37/04;C12N5/08;(IPC1-7):A61K39/00 |
主分类号 |
C12N5/06 |
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