CARDIAC MUSCLE REGENERATION USING MESENCHYMAL STEM CELLS
摘要
Disclosed is a method for producing cardiomyocytes in vivo by administering to the heart of an individual a cardiomyocyte producing amount of mesenchymal stem cells. These cells can be administered as a liquid injectible or as a preparation of cells in a matrix which is or becomes solid or semi-solid. The cells can be genetically modified to enhance myocardial differentiation and integration. Also disclosed is a method for replacing cells ex vivo in a heart valve for implantation.
申请公布号
WO9903973(A1)
申请公布日期
1999.01.28
申请号
WO1998US14520
申请日期
1998.07.14
申请人
OSIRIS THERAPEUTICS, INC.;PITTENGER, MARK, F.;GORDON, STEPHEN, L.;MACKAY, ALASTAIR, MORGAN
发明人
PITTENGER, MARK, F.;GORDON, STEPHEN, L.;MACKAY, ALASTAIR, MORGAN