POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM

摘要

The invention concerns medicines containing as active principle at least one compound of general formula (I) or one of its stereoisomers or its salts with a mineral or organic acid, the novel derivatives of formula (I), their stereoisomers, their salts with a mineral or organic acid and their preparation. In the general formula (I) Rc1 represents the chain (II) -CH(OR4)CH(OR3)CH(OR2)CH2OR1 and either Rc2 represents a hydrogen atom and either Rc3 represents the chain (III) -CH2CH(OR6)CH(OR7)CH2OR8 or Rc2 represents the chain (IV) -CH(OR5)CH(OR6)CH(OR7)CH2OR8 or (III) -CH2CH(OR6)CH(OR7)CH2OR8 and Rc3 represents a hydrogen atom, and 1 to 8 of substituents R1, R2, R3, R4, R5, R6, R7, R8, identical or different, represent a radical independently selected among the radicals a) -COR9, b)-COOR10, c)-CR11R12OCOR13, d)-CR11R12OR13, e)-CONR14R15, or f) one or several pairs of substituents R1, R2, R3, R4, R5, R6, R7, R8 consecutive or separated by one of the other substituents R2, R3, R6, R7 can also form a group: -C-(O)-; the other substituents R1, R2, R3, R4, R5, R6, R7, R8 representing hydrogen atoms.