摘要 |
Compounds of the present invention include cell growth inhibitors which are peptides of Formula (I):, A - B - D - E - F - (G)r - (K)s - L and acid salts thereof, wherein A, B, D, E, F, G and K are alpha -amino acid residues, and s and r are each, independently, 0 or 1. L is a monovalent radical, such as, for example, an amino group, an N-substituted amino group, a beta -hydroxylamino group, a hydrazido group, an alkoxy group, a thioalkoxy group, an aminoxy group, or an oximato group. The present invention also includes a method for treating cancer in a mammal, such as a human, comprising administering to the mammal an effective amount of a compound of Formula (I) in a pharmaceutically acceptable composition.
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申请人 |
BASF AKTIENGESELLSCHAFT;BASF BIORESEARCH CORPORATION;JANSSEN, BERND;BARLOZZARI, TERESA;HAUPT, ANDREAS;ZIERKE, THOMAS;KLING, ANDREAS |
发明人 |
JANSSEN, BERND;BARLOZZARI, TERESA;HAUPT, ANDREAS;ZIERKE, THOMAS;KLING, ANDREAS |