发明名称 DERIVATIVES OF BENZOFURANYLALKANE CARBOXYLIC ACID OR A MIXTURE OF THEIR ISOMERS, OR SEPARATE ISOMERS, OR THEIR SALTS
摘要 FIELD: organic chemistry. SUBSTANCE: invention relates to new derivatives of benzofuranylalkane carboxylic acid of the general formula (I): <EMI ID=0.213 HE=18 WI=39 TI=CHI> where R - a group of the formula OR where R - cycloalkyl, 6-membered saturated heterocycle; R - free or substituted phenyl; V - alkylene chain; W - tetrazolyl, group COR or CONR<SP>7</SP>R where R<SP>6</SP>R<SP>7</SP>,R - alkyl, cycloalkyl, phenyl, hydrogen. Synthesized compounds show antiinflammatory activity and can be used as drugs for treatment of patients with acute and chronic inflammatory processes. EFFECT: improved method of synthesis, enhanced effectiveness of compounds. 3 cl, 20 tbl, 290 ex
申请公布号 RU2125564(C1) 申请公布日期 1999.01.27
申请号 RU19940015838 申请日期 1994.05.05
申请人 BAJER AG 发明人 RJUDIGER FISHER;GABRIELE BROJNLIKH;KLAUS-KHEL'MUT MORS;RUDOL'F KHANKO;DZHON-EHDVARD BATLER-REHNSOKHOFF;MEHZEN EHS-ZAJED;GRAKHEM STERTON;STIV TADKHOUP;TREVOR EHBREM;UEHNDI MEHK DONAL'D-GIBSON
分类号 A61K31/34;A61K31/343;A61K31/38;A61P43/00;C07D307/80;C07D307/81;C07D333/60;C07D405/06;C07D405/10;C07D405/12;C07D407/12;C07D413/06;(IPC1-7):C07D307/80 主分类号 A61K31/34
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