| 摘要 |
Disclosed are novel antifungal agents having the formula: <IMAGE> as well as a pharmaceutically acceptable salt, ester of prodrug thereof, wherein R is: <IMAGE> -C(O)-R1 wherein R1 is alkyl, alkenyl, aryl, arylalkenyl, aryl-aryl-, arylalkoxy-aryl-, aryl-aryl-aryl-, arylkoxy-aryl-aryl-, or <IMAGE> wherein R2 is alkylamino, dialkylamino, (heterocyclic)alkyl, aryl, or arylalkyl; and X is O, NH, or NR3 wherein R3 is alkyl or aryl. Also disclosed are pharmaceutical compositions comprising a compound of the invention in combination with a pharmaceutically acceptable carrier; and a process for preparing the compounds of the invention.
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