发明名称 |
Antibodies which specifically bind mammalian receptors for interleukin-10 (IL-10) |
摘要 |
Receptor components for IL-10 are isolated and characterized. The amino acid sequence and nucleic acid encoding various species variants of the receptors are disclosed. Uses of the purified receptor gene and polypeptide are disclosed, including means for screening for agonists and antagonists of the receptor ligands, for producing diagnostic or therapeutic reagents, and for producing antibodies. Therapeutic or diagnostic reagents and kits are also provided.
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申请公布号 |
US5863796(A) |
申请公布日期 |
1999.01.26 |
申请号 |
US19950477166 |
申请日期 |
1995.06.07 |
申请人 |
SCHERING CORPORATION |
发明人 |
MOORE, KEVIN W.;LIU, YING;HO, ALICE SUK-YUE;HSU, DI-HWEI;BAZAN, J. FERNANDO;TAN, JIMMY C.;CHOU, CHUAN-CHU |
分类号 |
G01N33/577;A61K38/00;A61K39/395;A61P31/04;A61P37/00;C07H21/04;C07K14/54;C07K14/715;C12N5/10;C12N15/09;C12N15/12;C12P21/02;C12P21/08;C12R1/91;(IPC1-7):C07K16/28;C12N5/12;G01N33/53 |
主分类号 |
G01N33/577 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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