| 发明名称 |
Aryl pyrimidine derivatives |
| 摘要 |
The disclosed pyrimidine derivatives, and pharmaceutically acceptable salts and N-oxides thereof, exhibit useful pharmacological properties, in particular use as selective 5HT2B-antagonists. The invention is also directed to formulations and methods for treatment.
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| 申请公布号 |
US5863924(A) |
申请公布日期 |
1999.01.26 |
| 申请号 |
US19970858964 |
申请日期 |
1997.05.20 |
| 申请人 |
SYNTEX (U.S.A.) INC. |
发明人 |
BERGER, JACOB;FLIPPIN, LEE ALLEN;GREENHOUSE, ROBERT;JAIME-FIGUEROA, SAUL;LIU, YANZHOU;MILLER, AUBRY KERN;PUTMAN, DAVID GEORGE;WEINHARDT, KLAUS KURT;ZHAO, SHU-HAI |
| 分类号 |
A61K31/505;A61K31/506;A61K31/538;A61K31/55;A61P1/14;A61P9/12;A61P15/00;A61P25/00;A61P25/06;A61P25/20;A61P25/22;A61P25/24;A61P25/32;C07D239/42;C07D239/46;C07D239/48;C07D401/04;C07D401/12;C07D403/04;C07D405/04;C07D405/12;C07D409/04;C07D413/04;C07D473/32;(IPC1-7):C07D403/04 |
主分类号 |
A61K31/505 |
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