发明名称 Diagnostic imaging agent with backbone with modified sugar chain end
摘要 There is disclosed a diagnostic imaging agent which comprises a compound wherein at least one bifunctional ligand is chemically bonded to an amino group of amino oligosaccharide having the molecular weight of 500 to 2000 and having a reduction-treated reducing end of a sugar chain, or to an aldehyde group of a dialdehyde-oligosaccharide, at least one constituent monosaccharide of which is oxidation-cleaved, having the molecular weight of 500 to 2000 and having a reduction-treated reducing end of a sugar chain, and said ligand is coordinated with at least one metal ion selected from the group consisting of metal ions having the atomic number of 21-29, 31, 32, 37-39, 42-44, 49 and 56-83.
申请公布号 US5863518(A) 申请公布日期 1999.01.26
申请号 US19950544548 申请日期 1995.10.18
申请人 NIHON MEDI-PHYSICS CO., LTD. 发明人 HASHIGUCHI, YUJI;SUGINO, HIDEKI;KAMIMURA, KENJI;SERI, SHIGEMI
分类号 A61K47/48;A61K49/08;A61K49/12;(IPC1-7):A61K51/00;A61M36/14 主分类号 A61K47/48
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