| 摘要 |
PCT No. PCT/US93/11302 Sec. 371 Date Sep. 26, 1996 Sec. 102(e) Date Sep. 26, 1996 PCT Filed Nov. 19, 1993 PCT Pub. No. WO95/14006 PCT Pub. Date May 26, 1995 <IMAGE> (I) The present invention relates to a composition, and method of use, of an octahydrobenzo[f]quinoline-based compound represented by structural formula (I). In this formula, R1 is -OH or -OCH3 and R2 is -H, -OH or -OCH3. In addition, R3 is a C1 to C2 saturated or unsaturated, alkyl group. Furthermore, R4 is an aryl group, wherein examples of suitable aryl groups, as defined herein, include phenyl and thienyl groups. The method of this invention relates to the use of the claimed compositions to treat psychotic disorders, to treat Parkinson's disease, or to sedate a mammal by administering an effective amount of a claimed composition.
|
