Guard cartridge for chromatography

摘要

A new type of guard cartridge has been provided to prevent contamination of liquid chromatography (LC) columns by particulate and soluble contaminants. The cartridge is prepared by packing an empty tube with a chromatographic stationary phase and the packed tube is then sealed on both ends with porus sheets held in place by two collars. The cartridge gives minimum disturbance on column performance and significantly decreases the cost of production.