发明名称 MEDICAMENTS CONTENANT DES POLYHYDROXYBUTYLPYRAZINES, LES POLYHYDROXYBUTYLPYRAZINES NOUVELLES ET LEUR PREPARATION
摘要 The invention concerns medicines containing as active principle at least one compound of formula (I) in which: either (A) R9 and R10 represent each a -CH2OH radical and either R3 represents a methylene radical, R4 represents a -CHOH- radical and one of the radicals R1, R2, R5 and R6 represents a carbonyl, methylene, -CHF-, -CH(NHR7)- or -CH(OR8) radical and the others represent each a -CHOH-radical, or R2 and R5 represent each a -CHOH- radical, R3 represents a methylene radical and R1, R4 and R6 are identical and represent each a carbonyl, methylene, -CHF-, -CH(NHR7)- or -CH(OR8), or R1 and R6 represent each a -CHOH- radical, R3 represents a methylene radical and R2, R4 and R5 are identical and represent each a carbonyl, methylene, -CHF-, -CH(NHR7)- or -CH(OR8) radical, or R1, R4, R5 and R6 represent each a -CHOH- radical and -R2-R3- represents a -CH=CH-; or (B) R1, R2,, R4, R5 and R6 represent each a -CHOH- radical, R3 represents a methylene radical, R9 represents a -CH2F or -CH2OH radical, R10 represents a -CH2F or -CH2OH, provided that R9 and R10 are not both a -CH2OH radical or one of its stereoisomers or a salt of such a compound, the novel compounds of formula (I) and the method for preparing them.
申请公布号 FR2766183(A1) 申请公布日期 1999.01.22
申请号 FR19970009059 申请日期 1997.07.17
申请人 RHONE POULENC RORER SA 发明人 BASHIARDES GEORGES;CARRY JEAN CHRISTOPHE;EVERS MICHEL;FILOCHE BRUNO;MIGNANI SERGE
分类号 A61K31/495;A61K31/4965;A61K31/497;A61P3/10;C07D241/12;C07D405/14 主分类号 A61K31/495
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