3'-DEOXYRIBONUCLEOTIDE DERIVATIVES

摘要

3'-Deoxyribonucleotide derivatives represented by the following general formula ¢I!: Q-V-(CH2)n-NR-R wherein Q represents a 3'-deoxyribonucleotide residue; n is an integer of 4 or more; V represents -CC- or -CH=CH-; and R represents a fluorescent group. Because of having been improved in the uptake efficiency by RNA polymerases, these derivatives are useful as terminators in DNA base sequencing methods with the use of RNA polymerases.