发明名称 |
RESOLUTION OF AMINES |
摘要 |
The process comprises reacting the mixture consisting of 2-¢phenyl(1-methyl-1H-pyrazol-5-yl)methoxy!-N,N-dimethyl-etanamine (I) with an enanthiomer of an optically active acid in order to form a diasteroisomer salt, separating said salt and releasing the enantiomer from said compound (I). The dextrorotatory enantiomer of (I) can be obtained by reacting a racemic or non racemic mixture of (I) with (')-ditoluyl-L-tartaric acid, optionally mixed with ptoluensulfonic acid. The compound (I) has analgesic properties and its most active enantiomer is the destorotatory enantiomer.
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申请公布号 |
CA2295800(A1) |
申请公布日期 |
1999.01.21 |
申请号 |
CA19982295800 |
申请日期 |
1998.07.06 |
申请人 |
LABORATORIOS DEL DR. ESTEVE, S.A. |
发明人 |
FRIGOLA-CONSTANSA, JORDI;TORRENS-JOVER, ANTONI |
分类号 |
A61K31/415;A61P29/00;C07D231/12;(IPC1-7):C07D231/12 |
主分类号 |
A61K31/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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