发明名称 |
WA545 COMPOSITIONS |
摘要 |
Purified WA545 proteins and processes for producing them are disclosed. DNA molecules encoding the WA545 proteins are also disclosed. The proteins, members of the TGF-.beta. superfamily of growth factors, may be used to induce, enhance and/or inhibit the information, growth, proliferation, differentiation, maintenance of mesodermal tissue, including neural and muscle tissue. The proteins may also be useful for treatment of bone and cartilage and/or other connective tissue defects and in wound healing and related tissue repair.
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申请公布号 |
CA2295086(A1) |
申请公布日期 |
1999.01.21 |
申请号 |
CA19982295086 |
申请日期 |
1998.04.24 |
申请人 |
GENETICS INSTITUTE, INC.;THE WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH |
发明人 |
LAVALLIE, EDWARD R.;RACIE, LISA A.;SIVE, HAZEL;SUN, BENJAMIN |
分类号 |
C12N15/09;A61K38/00;A61K45/00;A61P17/02;A61P43/00;C07K14/46;C07K14/51;C07K16/22;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12P21/02;(IPC1-7):C12N15/12;A61K38/18;C12N15/62 |
主分类号 |
C12N15/09 |
代理机构 |
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地址 |
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