THIOFORMAMIDE DERIVATIVES OR THEIR PHARMACOLOGICALLY ACCEPTABLE SALTS

摘要

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of thioformamide of the general formula (I) where Y - a group of the formula -C(O)-, -CH(OH)-, =N-O-Ph, O=C(Ph)-O; Z means ; A means substituted or nonsubstituted imidazopyridyl; R1, R2, R and R - hydrogen or lower alkyl, or their pharmaceutically acceptable salts exhibiting high hypotensive properties. EFFECT: improved method of synthesis, enhanced pharmacological activity of compounds. 6 cl, 24 ex, 1 tbl