Heterocyclic substituted pyrrolidine amide derivatives

摘要

The present invention relates to novel heterocyclic substituted pyrrolidine amide derivatives of formula (1), <IMAGE> formula (1) and stereoisomers and pharmaceutically acceptable salts thereof and their use as tachykinin receptor antagonists. Such antagonists are useful in the treatment of tachykinin-mediated diseases and conditions disclosed herein including: asthma, cough, and bronchitis.