发明名称 |
Substituted pyridines as selective cyclooxygenase-2 inhibitors |
摘要 |
The invention encompasses the novel compound of Formula I as well as a method of treating COX-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I. <IMAGE> I The invention also encompasses certain pharmaceutical compositions for treatment of COX-2 mediated diseases comprising compounds of Formula I.
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申请公布号 |
US5861419(A) |
申请公布日期 |
1999.01.19 |
申请号 |
US19970893395 |
申请日期 |
1997.07.11 |
申请人 |
MERCK FROSST CANAD, INC. |
发明人 |
DUBE, DANIEL;FRIESEN, RICHARD;FORTIN, REJEAN;WANG, ZHAOYIN;GAUTHIER, JACQUES YVES |
分类号 |
A61K31/44;A61K31/444;A61K31/655;C07D213/04;C07D213/22;C07D213/26;C07D213/34;C07D213/36;C07D213/44;C07D213/54;C07D213/61;C07D213/65;C07D213/75;C07D213/80;C07D213/85;C07D213/89;(IPC1-7):A61K31/44 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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