发明名称 Substituted pyridines as selective cyclooxygenase-2 inhibitors
摘要 The invention encompasses the novel compound of Formula I as well as a method of treating COX-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I. <IMAGE> I The invention also encompasses certain pharmaceutical compositions for treatment of COX-2 mediated diseases comprising compounds of Formula I.
申请公布号 US5861419(A) 申请公布日期 1999.01.19
申请号 US19970893395 申请日期 1997.07.11
申请人 MERCK FROSST CANAD, INC. 发明人 DUBE, DANIEL;FRIESEN, RICHARD;FORTIN, REJEAN;WANG, ZHAOYIN;GAUTHIER, JACQUES YVES
分类号 A61K31/44;A61K31/444;A61K31/655;C07D213/04;C07D213/22;C07D213/26;C07D213/34;C07D213/36;C07D213/44;C07D213/54;C07D213/61;C07D213/65;C07D213/75;C07D213/80;C07D213/85;C07D213/89;(IPC1-7):A61K31/44 主分类号 A61K31/44
代理机构 代理人
主权项
地址