| 摘要 |
PROBLEM TO BE SOLVED: To obtain the subject stable aqueous solution preparation by admixingβ-lactoglobulin (β-LG) and human calcuitonin (h-CT). SOLUTION: This preparation is obtained by formulatingβ-LG one of protein components in milk to an aqueous solution of h-CT. In the production of this preparation,β-LG is dissolved in a suitable aqueous solvent as distilled water or tap water, the pH of the solution is adjusted to <=4, then h-CT is dissolved therein. The concentration of h-CT is suitably 0.5-10 mg/ml,β-LG is 1-40 mg/ml, suitably. This preparation may contain a mucous absorption promoter, stimulation alleviator, isotonizing agent, thickener, preservative and other additives. Sinceβ-LG is formulated, the preparation is stable since its coagulation of h-CT is delayed.
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