Method of the specific immunoassay of human plasma glutathione peroxidase, kit for its implementation, oligopeptides and antibodies specific for the method

摘要

PCT No. PCT/FR94/01031 Sec. 371 Date May 2, 1995 Sec. 102(e) Date May 2, 1995 PCT Filed Sep. 1, 1994 PCT Pub. No. WO95/06719 PCT Pub. Date Mar. 9, 1995An oligopeptide having an amino acid sequence Glu Pro Gly Asn Ser Glu Ile Leu Pro Thr Leu Lys and variants thereof; immunogenic conjugates obtained therefrom; antibodies produced by means of said conjugates and which specifically recognize human plasma glutathione peroxidase (pl.GPx); methods for assaying human plasma glutathione peroxidase (pl.GPx); and assaying kits. The invention is useful in the medical diagnosis, treatment and monitoring of pathologic conditions induced by a variation in pl.GPx, for example, hepatic tumors, acute rejection of renal or hepatic graft, renal insufficiency and selenium deficiency.