| 发明名称 |
Process for the synthesis of 2'-O-substituted pyrimidines |
| 摘要 |
Improved processes for the synthesis of 2'-O-substituted pyrimidine nucleosides are provided. The processes feature alkylation of a 2,2'-anhydropyrimidine nucleoside or a 2S,2'-anhydropyrimidine nucleoside with a weak nucleophile in the presence of a Lewis acid.
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| 申请公布号 |
US5861493(A) |
申请公布日期 |
1999.01.19 |
| 申请号 |
US19970890084 |
申请日期 |
1997.07.09 |
| 申请人 |
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发明人 |
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| 分类号 |
C07H19/067;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7064;A61K31/7068;A61K31/7072;A61K31/7088;A61K31/712;A61K48/00;A61P31/12;A61P31/18;A61P35/00;A61P37/04;C07H19/06;C07H19/09;C07H19/10;C07H21/00;C12N15/09;(IPC1-7):C07H19/00;C07H21/02 |
主分类号 |
C07H19/067 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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